Seroquel and Appetite: Understanding the Link and Potential Loss

Seroquel, also known as quetiapine, is an antipsychotic medication commonly used to treat mental health conditions such as schizophrenia, bipolar disorder, and major depressive disorder. While it can be highly effective in managing these conditions, it is not without side effects. One of the most commonly reported side effects is changes in appetite, which can lead to weight gain or loss. This article will delve into the link between Seroquel and appetite, and how it can potentially lead to appetite loss.

How Does Seroquel Affect Appetite?

Seroquel can affect appetite in different ways. Some people may experience an increase in appetite, leading to weight gain. This is often due to the medication’s effect on certain chemicals in the brain that control hunger. However, others may experience a decrease in appetite, leading to weight loss. This is less common but can occur, particularly in the early stages of treatment or when the dosage is changed.

Why Does Seroquel Cause Appetite Loss?

The exact reason why Seroquel can cause appetite loss is not fully understood. It is believed to be related to the medication’s effect on the brain’s neurotransmitters, particularly dopamine and serotonin, which play a role in regulating appetite. Additionally, some people may experience gastrointestinal side effects such as nausea or upset stomach, which can reduce the desire to eat.

What Can Be Done to Manage Appetite Changes?

If you’re experiencing appetite changes while taking Seroquel, it’s important to discuss this with your healthcare provider. They may be able to adjust your dosage or switch you to a different medication. Additionally, maintaining a healthy diet and regular exercise can help manage weight changes. It’s also important to monitor your weight regularly and report any significant changes to your healthcare provider.

Is Appetite Loss a Serious Side Effect?

While appetite loss can be concerning, it’s not typically considered a serious side effect of Seroquel. However, if it leads to significant weight loss or if you’re unable to maintain a healthy weight, it can become a serious issue. In such cases, it’s important to seek medical attention.


While Seroquel can cause changes in appetite, including potential appetite loss, these side effects can often be managed with the help of your healthcare provider. It’s important to communicate any changes in appetite or weight to your healthcare provider, so they can help you find the best solution for your situation. Remember, the goal of treatment is not just to manage symptoms, but also to maintain overall health and well-being.